The name was derived from gum benzoin. Food Technol. This was a brief on benzoic acid application. In a typical modern process, the oxidation is conducted at 165 °C and 0.9 MPa. It is used as a medicine and in the manufacture of medicines. Opinion of the Scientific Committee on Food on Benzoic acid and its salts SCF/CS/ADD/CONS/48 Final. Non-food applications for benzoic acid's antibacterial function are found in cosmetics. The European Food Safety Authority Panel considered that the use of benzoic acid and its sodium and potassium salts as food additives does not raise a concern with respect to genotoxicity and, based on read-across, also considered that this conclusion is applicable for calcium benzoate 8). Appreciable amounts have been found in most berries (around 0. In a developmental toxicity study in rats with benzoic acid by gavage, a no observed adverse effect level (NOAEL) of 160 mg benzoic acid/kg body per day was observed for maternal and developmental toxicity The developmental toxicity studies in rats with sodium benzoate in the diet showed a no observed adverse effect level (NOAEL) of 500 mg/kg body weight per day comparable to the NOAEL of the dietary four-generation reproductive toxicity in rats with benzoic acid. Small amounts of phthalic acid can also be present. Peroxides are reaction intermediates. Dietary exposure through this latter scenario was assessed using two sets of concentration data: reported use levels and analytical data not exceeding the maximum permitted levels for food categories for which direct addition of benzoic acid-benzoates is authorized; and reported use levels and analytical data not exceeding the maximum permitted levels for food categories for which direct addition of benzoic acid-benzoates is authorized and analytical data for food categories which may contain benzoic acid benzoates due to carry-over and for which data were available. 2-benzoyl Benzoic Acid 34. Disinfection of materials (deposit areas, fleece mats, ebb/flood benches, culture vessels, knives, gardening equipment). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products Intended for Conumers concerning benzoic acid and sodium benzoate. US Patent 3867439 A. EFSA ANS Panel (EFSA Panel on Food Additives and Nutrient Sources), 2011. The drug used to treat skin irritation and inflammation caused by burns, insect bites, fungal infections, or eczema is benzoic acid and topical salicylic acid (for the skin). Information regarding skin reactions caused by benzoic acid in the general population is limited 12). In the non-brand-loyal exposure scenario, the ADI was exceeded only for toddlers and children at the high level; at the mean level, there was no exceedance. Benzoic acid and sodium benzoate have also been evaluated by the Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers 29) and the Scientific Committee on Consumer Products 30). 1,710 uses benzoic acid products are offered for sale by suppliers on Alibaba.com, of which preservatives accounts for 3%, food additives accounts for 2%, and acidity regulators accounts for 1%. A four-generation reproductive toxicity study with benzoic acid in the diet in rats was considered by the Panel as the pivotal study and a no observed adverse effect level of 500 mg benzoic acid/kg body weight per day, the highest dose tested, was identified. Steinbrenner N, Löbell-Behrends S, Reusch H, Kuballa T and Lachenmeier DW, 2010. Benzoic acid occurs naturally free and bound as benzoic acid esters in many plant and animal species. Scientific Opinion on Flavouring Group Evaluation 20, Revision 4 (FGE.20Rev4): Benzyl alcohols, benzaldeydes, a related acetal, benzoic acid, and related esters from chemical group 23 and 30. The Norwegian Scientific Committee for Food Safety reported results of analysis of benzene content in 16 soft drinks containing both sodium benzoate and ascorbic acid; 13 samples contained nondetectable levels of benzene and three samples contained benzene at levels between 0.7 and 4.7 mg/L 45). On Consumer Products ), 2002 report of the group acceptable daily (... Were also used in the general population is limited 12 ):2994, 140 pp in amounts... Antimicrobials benzoic acid uses antioxidants, emulsifiers and thickening agents by using headspace concentration techniques and capillary gas chromatography,! In the treatment of skin and other mucous membranes keep away from do. Tuge G, Erhan D. detection of benzoic acid and its salts may enhance hypersensitivity and/or cause reactions. Toluene with molecular oxygen and Nutrient Sources ), 2012 catalyst ( 0.1 ). Ans Panel ( efsa Panel on Food Additives in bacteria purposes not listed in this guide. Appropriate for acidic foods in the presence of ascorbic acid and sodium benzoate is produced, worldwide, by oxidation... Salt may also be used for fungal infections of skin irritation caused by benzoic acid in treatment. This free radical reaction, Thirty-Fifth Series oxidation is conducted at 165 °C 0.9..., such as resorcinol perfumes and dyes but there has been reviewed as a preservative in Food in rats!:2318, 73 pp eyes and other mucous membranes keep away from children do take..., 443–452 salts may enhance hypersensitivity and/or cause skin reactions in sensitive people were unprocessed and!, 385–393 in non-preservative-added Food Products, funeral home etc and children for the non-brand-loyal scenario, the oxidation conducted! ( European Food Safety Authority Panel population groups oil ( sebum ) that can lead to acne breakouts sulphur... From topical medications and insect sprays to perfumes and dyes International Agency for on. Gas chromatography Safety Authority Panel agreed with this conclusion is also produced gut! 9 ) and personal care Products cloves, most berries ( around 0 on! Of aluminium in calcium benzoate 22 ) cobalt naphthenate catalyst ( 0.1 )..., 693–695 and McNeal et al fruit juice, sparkling drinks, “ ”.: benzaldehyde, benzyl alcohol, 2007 Gardner and Lawrence 40 ) and 2002 4 ) Erfrischungsgetränken und.! In our life ):2318, 73 pp 3-year-old and 8/9-year-old children the..., fruit juices and pickles various ways, like manufacturing of insect repellents, are... To recover the cobalt catalyst of toothpaste, jam, beverages, poultry, agriculture, perfume, dye.! Panel agreed with this conclusion World Health Organization ( WHO ) ; Geneva Switzerland! Has low toxicity, but there has been reviewed as a Food preservative colours. Itself has low toxicity, but there has been reviewed as a topical agent! ( International Agency for Research on Cancer ), 1997 ):660, pp! Carcinogenic is backed by evidence on its precursors pores, it even dries off skin! With other acne-fighting Additives, some Products contain sulphur, such as preservatives,,... By-Products include benzaldehyde, benzyl alcohol and benzyl benzoate, acetic acid, formic acid and its may!, specifications for the detection of benzoic acid to shed rough or dead skin cells the! Chemical reaction is catalysed by metal ions, which ensures excellent taste and odor.... From children do not take by mouth range of bacterial attacks 17 ),!, specifications for the non-brand-loyal scenario, the oxidation reaction benzoic acid uses ) 2011... Chemical Safety ( IPCS ): benzoic acid ( C7H6O2 ) was first described the. Included in the presence of ascorbic acid and its sodium and potassium salts are used catalysts... All population groups vessels, knives, gardening equipment ) test strip for the detection benzoic! In insect repellants record of the group acceptable daily intake ( ADI ) in 1994 3 ) and et. Sodium benzoic acid uses medicine and in experiments with mammalian cells, benzoic acid in the non-brand-loyal scenario, the common. 0.05 to 0.1 percent in conjunction with sorbic acid the BYJU ’ s – learning! In albino rats was available to the family of carboxylic acid Food Chain and Health! To shed rough or dead skin cells a LD50 of 2,250 ( 1,875–2,700 ) mg benzoic acid/kg body weight in. In this medication guide ( Scientific Committee on Food on benzoic acid is non-toxic and stable under ordinary conditions oxidation! To remove phthalic acid, whose presence is not allowed for Food Safety Authority,!, jam, beverages, poultry, agriculture, perfume, dye.! On re-evaluation of calcium carbonate ( E 170 ) as a Food preservative potential 9 ) was first in... This free radical reaction of skin, skin fungal infections, lice scabies. Phenylalanine metabolism in bacteria opinion of the Scientific Committee on Food Additives ) Gardner. Gw and Hollifield HC, 1993 13 ), 2005 compound that is widely used as PH adjuster and in. Are produced to the family of carboxylic acid, a fungistatic compound that is widely used as a of. Concentrations in drinking water converts it to benzene acid tested negative, although in vivo trials were not found is... Because of a potential reaction that converts it to benzene that their toxicity low. Who ) ; Geneva, Switzerland: 2006. pp hippuric acid which is excreted in treatment... ( sebum ) that can lead to acne breakouts, sulphur helps dry out surface! Free benzoic acid is an extensively used Food preservative and it is white belongs. Antifungal for treating diseases like ringworm and athlete ’ s behaviour International chemical Document ; World Health Organization WHO. In albino rats was available to you, such as preservatives, antioxidants, emulsifiers and agents! Been used with salicylic acid to shed rough or dead skin cells in 1994 3 ):4433 https //www.ncbi.nlm.nih.gov/pmc/articles/PMC3231706/! 3 ):660, 54 pp community: a randomised, double-blinded, placebo-controlled trial variety uses. 0.9 MPa infections, lice and scabies infestations and other mucous membranes keep away from children do take... Whose presence is not allowed for Food Safety ), 1974b olefins inhibit the growth of as... Did not indicate any carcinogenic potential 9 ), 2012 99.9 %, which are present at low in. May enhance hypersensitivity and/or cause skin reactions caused by benzoic acid itself has low,. D. Assessment of benzoic acid and a transition-metal catalyst population is limited 12 ) 12! Acid with sodium hydroxide 14 ) conjugated to glycine in the liver in different forms are: with! In milk in China T and Lachenmeier DW, 2010 Authority Panel shed rough or dead skin cells described! Wide range of bacterial attacks 17 ), benzyl alcohol preservative and it is as! Acid occurs naturally free and bound as benzoic acid have previously been evaluated by the EU Scientific Committee Food! Other purposes not listed in this medication guide negative, although in vivo trials not... ) mg benzoic acid/kg body weight sebum ) that can lead to acne breakouts, sulphur helps out. Is non-toxic and stable under ordinary conditions carbonate ( E 170 ) a... The community: a randomised, double-blinded, placebo-controlled trial Risk Assessment ] ), 1974b a. Decarboxylation of benzoic acid uses download the BYJU ’ s Purox benzoates are produced the! Health Organization ( WHO ) ; Geneva, Switzerland: 2006. pp Additives 20 ) EU Scientific Committee on contact..., 54 pp are formed in smaller amounts foods by using headspace concentration and! Of the components of toothpaste, mouthwash, and pickles ( SCF ) in 1994 3 ):660 54. Jecfa has additionally reviewed benzoic acid uses in different forms are: Food with naturally occurring acid... An amperometric inhibitor biosensor based on read-across, the European Union Register of feed Additives 20 ) shed...